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7,8,9,10-Tetrahydrobenzo[pqr]tetraphen-7-ol

CAS: 6272-55-5 F: C20H16O W: 272.34

7,8,9,10-Tetrahydrobenzopyren-7-ol is a benzopyrene derivative that is activated by hepatic cytosol into electrophilic s
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Bioactivity 7,8,9,10-Tetrahydrobenzo[a]pyren-7-ol is a benzopyrene derivative that is activated by hepatic cytosol into electrophilic sulfuric acid esters[1], which are capable of forming covalent DNA adducts and inducing mutations[2].
Name 7,8,9,10-Tetrahydrobenzo[pqr]tetraphen-7-ol
CAS 6272-55-5
Formula C20H16O
Molar Mass 272.34
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Glatt H, Pauly K, Frank H, Seidel A, Oesch F, Harvey RG, Werle-Schneider G. Substance-dependent sex differences in the activation of benzylic alcohols to mutagens by hepatic sulfotransferases of the rat. Carcinogenesis. 1994 Nov;15(11):2605-11. [2]. Surh YJ, Tannenbaum SR. Sulfotransferase-mediated activation of 7,8,9,10-tetrahydro-7-ol, 7,8-dihydrodiol, and 7,8,9,10-tetraol derivatives of benzo[a]pyrene. Chem Res Toxicol. 1995 Jul-Aug;8(5):693-8.